piwik-script

English Intern
    Systemmedizin

    Publikationen

    2018

    1. Maurus, Katja, Silke Appenzeller, Sabine Roth, Jochen Kuper, Simone Rost, Svenja Meierjohann, Panagiota Arampatzi, Matthias Goebeler, Andreas Rosenwald, Eva Geissinger, and Marion Wobser. “Panel Sequencing Shows Recurrent Genetic FAS Alterations in Primary Cutaneous Marginal Zone Lymphoma.” Journal of Investigative Dermatology 138, no. 7 (July 1, 2018): 1573–81. https://doi.org/10.1016/j.jid.2018.02.015.
    2. Holmqvist, Erik, Lei Li, Thorsten Bischler, Lars Barquist, and Jörg Vogel. “Global Maps of ProQ Binding In Vivo Reveal Target Recognition via RNA Structure and Stability Control at MRNA 3′ Ends.” Molecular Cell 70, no. 5 (June 7, 2018): 971-982.e6. https://doi.org/10.1016/j.molcel.2018.04.017.
    3. Bury, Susanne, Manonmani Soundararajan, Richa Bharti, Rudolf von Bünau, Konrad U. Förstner, and Tobias A. Oelschlaeger. “The Probiotic Escherichia Coli Strain Nissle 1917 Combats Lambdoid Bacteriophages Stx and λ.” Frontiers in Microbiology 9 (May 29, 2018). https://doi.org/10.3389/fmicb.2018.00929.
    4. Cochain, Clément, Ehsan Vafadarnejad, Panagiota Arampatzi, Pelisek Jaroslav, Holger Winkels, Klaus Ley, Dennis Wolf, Antoine-Emmanuel Saliba, and Alma Zernecke. “Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis.” Circulation Research, March 15, 2018, CIRCRESAHA.117.312509. https://doi.org/10.1161/CIRCRESAHA.117.312509.
    5. Li, Lei, Konrad U. Förstner, and Yanjie Chao. “Computational Analysis of RNA–Protein Interactions via Deep Sequencing.” In Transcriptome Data Analysis, 171–82. Methods in Molecular Biology. Humana Press, New York, NY, 2018. https://doi.org/10.1007/978-1-4939-7710-9_12.
    6. Dugar, Gaurav, Ryan T. Leenay, Sara K. Eisenbart, Thorsten Bischler, Belinda U. Aul, Chase L. Beisel, and Cynthia M. Sharma. “CRISPR RNA-Dependent Binding and Cleavage of Endogenous RNAs by the Campylobacter Jejuni Cas9.” Molecular Cell 69, no. 5 (March 1, 2018): 893-905.e7. https://doi.org/10.1016/j.molcel.2018.01.032.
    7. El-Hossary, Ebaa M., Konrad U. Förstner, Patrice François, Damien Baud, Karin Streker, Jacques Schrenzel, Knut Ohlsen, and Ulrike Holzgrabe. “A Novel Mechanism of Inactivating Antibacterial Nitro Compounds in the Human Pathogen Staphylococcus Aureus by Overexpression of a NADH-Dependent Flavin Nitroreductase.” Antimicrobial Agents and Chemotherapy 62, no. 2 (February 1, 2018): e01510-17. https://doi.org/10.1128/AAC.01510-17.

    2017

    1. Prasse, Daniela, Konrad U. Förstner, Dominik Jäger, Rolf Backofen, and Ruth A. Schmitz. “SRNA154 a Newly Identified Regulator of Nitrogen Fixation in Methanosarcina Mazei Strain Gö1.” RNA Biology 14, no. 11 (November 2, 2017): 1544–58. https://doi.org/10.1080/15476286.2017.1306170.
    2. Krohn-Molt, Ines, Malik Alawi, Konrad U. Förstner, Alena Wiegandt, Lia Burkhardt, Daniela Indenbirken, Melanie Thieß, Adam Grundhoff, Julia Kehr, Andreas Tholey, and Wolfgang R. Streit. “Insights into Microalga and Bacteria Interactions of Selected Phycosphere Biofilms Using Metagenomic, Transcriptomic, and Proteomic Approaches.” Frontiers in Microbiology 8 (October 10, 2017). https://doi.org/10.3389/fmicb.2017.01941.
    3. Wedel, Carolin, Konrad U. Förstner, Ramona Derr, and T. Nicolai Siegel. “GT‐rich Promoters Can Drive RNA Pol II Transcription and Deposition of H2A.Z in African Trypanosomes.” The EMBO Journal 36, no. 17 (September 1, 2017): 2581–94. https://doi.org/10.15252/embj.201695323.
    4. Schartner, Christoph, Claus-Jürgen Scholz, Heike Weber, Antonia Post, Florian Freudenberg, Lena Grünewald, and Andreas Reif. “The Regulation of Tetraspanin 8 Gene Expression—A Potential New Mechanism in the Pathogenesis of Bipolar Disorder.” American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 174, no. 7 (August 4, 2017): 740–50. https://doi.org/10.1002/ajmg.b.32571.
    5. Galuppo, Paolo, Sabine Vettorazzi, Julian Hövelmann, Claus-Jürgen Scholz, Jan Peter Tuckermann, Johann Bauersachs, and Daniela Fraccarollo. “The Glucocorticoid Receptor in Monocyte-Derived Macrophages Is Critical for Cardiac Infarct Repair and Remodeling.” The FASEB Journal 31, no. 11 (August 2, 2017): 5122–32. https://doi.org/10.1096/fj.201700317R.
    6. Wunsch, Marie, Samir Jabari, Barbara Voussen, Michael Enders, Shanthi Srinivasan, François Cossais, Thilo Wedel, Martina Boettner, Anna Schwarz, Linda Weyer, Oktay Göcer, Michael Schroeter, Mathias Maeurer, Matthias Woenckhaus, Karolin Pollok, Helena Radbruch, Luisa Klotz, Claus-Jürgen Scholz, Joachim Nickel, Andreas Friebe, Klaus Addicks, Süleyman Ergün, Paul V. Lehmann, and Stefanie Kuerten. “The Enteric Nervous System Is a Potential Autoimmune Target in Multiple Sclerosis.” Acta Neuropathologica 134, no. 2 (August 1, 2017): 281–95. https://doi.org/10.1007/s00401-017-1742-6.
    7. Bail, Kathrin, Quirin Notz, Damiano M. Rovituso, Andrea Schampel, Marie Wunsch, Tobias Koeniger, Verena Schropp, Richa Bharti, Claus-Juergen Scholz, Konrad U. Foerstner, Christoph Kleinschnitz, and Stefanie Kuerten. “Differential Effects of FTY720 on the B Cell Compartment in a Mouse Model of Multiple Sclerosis.” Journal of Neuroinflammation 14 (July 24, 2017): 148. https://doi.org/10.1186/s12974-017-0924-4.
    8. Remes, B., T. Rische-Grahl, K. M. H. Müller, K. U. Förstner, Sung-Huan Yu, L. Weber, A. Jäger, V. Peuser, and G. Klug. “An RpoHI-Dependent Response Promotes Outgrowth after Extended Stationary Phase in the Alphaproteobacterium Rhodobacter Sphaeroides.” Journal of Bacteriology 199, no. 14 (July 15, 2017): e00249-17. https://doi.org/10.1128/JB.00249-17.
    9. Sharan, Malvika, Konrad U. Förstner, Ana Eulalio, and Jörg Vogel. “APRICOT: An Integrated Computational Pipeline for the Sequence-Based Identification and Characterization of RNA-Binding Proteins.” Nucleic Acids Research 45, no. 11 (June 20, 2017): e96–e96. https://doi.org/10.1093/nar/gkx137.
    10. Müller, E., S. Bauer, T. Stühmer, A. Mottok, C.-J. Scholz, T. Steinbrunn, D. Brünnert, A. Brandl, H. Schraud, S. Kreßmann, A. Beilhack, A. Rosenwald, R. C. Bargou, and M. Chatterjee. “Pan-Raf Co-Operates with PI3K-Dependent Signalling and Critically Contributes to Myeloma Cell Survival Independently of Mutated RAS.” Leukemia 31, no. 4 (April 31, 2017): 922–33. https://doi.org/10.1038/leu.2016.264.
    11. Schampel, Andrea, Oleg Volovitch, Tobias Koeniger, Claus-Jürgen Scholz, Stefanie Jörg, Ralf A. Linker, Erhard Wischmeyer, Marie Wunsch, Johannes W. Hell, Süleyman Ergün, and Stefanie Kuerten. “Nimodipine Fosters Remyelination in a Mouse Model of Multiple Sclerosis and Induces Microglia-Specific Apoptosis.” Proceedings of the National Academy of Sciences 114, no. 16 (April 18, 2017): E3295–3304. https://doi.org/10.1073/pnas.1620052114.
    12. Lavysh, Daria, Maria Sokolova, Marina Slashcheva, Konrad U. Förstner, and Konstantin Severinov. “Transcription Profiling of Bacillus Subtilis Cells Infected with AR9, a Giant Phage Encoding Two Multisubunit RNA Polymerases.” MBio 8, no. 1 (March 8, 2017): e02041-16. https://doi.org/10.1128/mBio.02041-16.
    13. Chao, Yanjie, Lei Li, Dylan Girodat, Konrad U. Förstner, Nelly Said, Colin Corcoran, Michał Śmiga, Kai Papenfort, Richard Reinhardt, Hans-Joachim Wieden, Ben F. Luisi, and Jörg Vogel. “In Vivo Cleavage Map Illuminates the Central Role of RNase E in Coding and Non-Coding RNA Pathways.” Molecular Cell 65, no. 1 (January 5, 2017): 39–51. https://doi.org/10.1016/j.molcel.2016.11.002.

    2016

    1. Saliba AE, Li L, Westermann AJ, Appenzeller S, Stapels DA, Schulte LN, Helaine S, Vogel J. Single-cell RNA-seq ties macrophage polarization to growth rate of intracellular Salmonella. Nat Microbiol. 2016 Nov 14;2:16206
    2. van Hulzen KJ, Scholz CJ, Franke B, Ripke S, Klein M, McQuillin A, Sonuga-Barke EJ; PGC ADHD Working Group., Kelsoe JR, Landén M, Andreassen OA; PGC Bipolar Disorder Working Group., Lesch KP, Weber H, Faraone SV, Arias-Vasquez A, Reif A. Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis. Biol Psychiatry. 2016 Oct 18. pii: S0006-3223(16)32920-1
    3. Berger P, Knödler M, Förstner KU, Berger M, Bertling C, Sharma CM, Vogel J,
      Karch H, Dobrindt U, Mellmann A. The primary transcriptome of the Escherichia
      coli O104:H4 pAA plasmid and novel insights into its virulence gene expression
      and regulation. Sci Rep. 2016 Oct 17;6:35307. doi: 10.1038/srep35307
    4. Smirnov A, Förstner KU, Holmqvist E, Otto A, Günster R, Becher D, Reinhardt R, Vogel J. Grad-seq guides the discovery of ProQ as a major small RNA-binding protein. Proc Natl Acad Sci U S A. 2016 Sep 26. pii: 201609981. [Epub ahead of print] PubMed PMID: 27671629.
    5. Müller E, Bauer S, Stühmer T, Mottok A, Scholz CJ, Steinbrunn T, Brünnert D, Brandl A, Schraud H, Kreßmann S, Beilhack A, Rosenwald A, Bargou RC, Chatterjee M. Pan-Raf co-operates with PI3K-dependent signalling and critically contributes to myeloma cell survival independently of mutated RAS. Leukemia. 2016 Sep 30. doi: 10.1038/leu.2016.264.
    6. Babski J, Haas KA, Näther-Schindler D, Pfeiffer F, Förstner KU, Hammelmann M, Hilker R, Becker A, Sharma CM, Marchfelder A, Soppa J. Genome-wide identification of transcriptional start sites in the haloarchaeon Haloferax volcanii based on differential RNA-Seq (dRNA-Seq). BMC Genomics. 2016 Aug 12;17(1):629. doi: 10.1186/s12864-016-2920-y. PubMed PMID: 27519343; PubMed Central PMCID: PMC4983044.
    7. Dingemans J, Monsieurs P, Yu SH, Crabbé A, Förstner KU, Malfroot A, Cornelis P, Van Houdt R. Effect of Shear Stress on Pseudomonas aeruginosa Isolated from the Cystic Fibrosis Lung. MBio. 2016 Aug 2;7(4). pii: e00813-16. doi: 10.1128/mBio.00813-16. PubMed PMID: 27486191; PubMed Central PMCID: PMC4981712
    8. Braun M, Ress ML, Yoo YE, Scholz CJ, Eyrich M, Schlegel PG, Wölfl M. IL12-mediated sensitizing of T-cell receptor-dependent and -independent tumor cell killing. Oncoimmunology. 2016 May 19;5(7):e1188245. doi: 10.1080/2162402X.2016.1188245. eCollection 2016 Jul. PubMed PMID: 27622043; PubMed Central PMCID: PMC5006926.
    9. Cao Y, Förstner KU, Vogel J, Smith CJ. Cis-encoded sRNAs, a conserved mechanism for repression of polysaccharide utilization in the Bacteroides. J Bacteriol. 2016 Jun 27. pii: JB.00381-16. [Epub ahead of print] PubMed PMID: 27353652.
    10. Meier D, Kruse J, Buttlar J, Friedrich M, Zenk F, Boesler B, Förstner KU, Hammann C, Nellen W. Analysis of the Microprocessor in Dictyostelium: The Role of RbdB, a dsRNA Binding Protein. PLoS Genet. 2016 Jun 6;12(6):e1006057. doi: 10.1371/journal.pgen.1006057. eCollection 2016 Jun. PubMed PMID: 27272207.
    11. Das S, Lindemann C, Young BC, Muller J, Österreich B, Ternette N, Winkler AC, Paprotka K, Reinhardt R, Förstner KU, Allen E, Flaxman A, Yamaguchi Y, Rollier CS, van Diemen P, Blättner S, Remmele CW, Selle M, Dittrich M, Müller T, Vogel J, Ohlsen K, et al. Natural mutations in a Staphylococcus aureus virulence regulator attenuate cytotoxicity but permit bacteremia and abscess formation. Proc Natl Acad Sci U S A. 2016 May 31;113(22):E3101-10. doi: 10.1073/pnas.1520255113. Epub 2016 May 16. PubMed [citation] PMID: 27185949
    12. Vucicevic D, Gehre M, Dhamija S, Friis-Hansen L, Meierhofer D, Sauer S, Ørom UA. The long non-coding RNA PARROT is an upstream regulator of c-Myc and affects proliferation and translation. Oncotarget. 2016 Apr 25. doi: 10.18632/oncotarget.8985. [Epub ahead of print] PubMed [citation] PMID: 27129154
    13. Moratin J, Hartmann S, Brands R, Brisam M, Mutzbauer G, Scholz C, Seher A, Müller-Richter U, Kübler AC, Linz C. Evaluation of miRNA-expression and clinical tumour parameters in oral squamous cell carcinoma (OSCC). J Craniomaxillofac Surg. 2016 Apr 22. pii: S1010-5182(16)30026-9. doi: 10.1016/j.jcms.2016.04.017.[Epub ahead of print] PubMed PMID: 27210505.
    14. Hesbacher S, Pfitzer L, Wiedorfer K, Angermeyer S, Borst A, Haferkamp S, Scholz CJ, Wobser M, Schrama D, Houben R. RB1 is the crucial target of the Merkel cell polyomavirus Large T antigen in Merkel cell carcinoma cells. Oncotarget. 2016 Apr 18. doi: 10.18632/oncotarget.8793. [Epub ahead of print] PubMed [citation] PMID: 27121059
    15. Cuklina J, Hahn J, Imakaev M, Omasits U, Förstner KU, Ljubimov N, Goebel M, Pessi G, Fischer HM, Ahrens CH, Gelfand MS, Evguenieva-Hackenberg E. Genome-wide transcription start site mapping of Bradyrhizobium japonicum grown free-living or in symbiosis - a rich resource to identify new transcripts, proteins and to study gene regulation. BMC Genomics. 2016 Apr 23;17(1):302. doi: 10.1186/s12864-016-2602-9. PubMed [citation] PMID: 27107716, PMCID: PMC4842269
    16. Weidner C, Rousseau M, Plauth A, Wowro SJ, Fischer C, Abdel-Aziz H, Sauer S. Iberis amara Extract Induces Intracellular Formation of Reactive Oxygen Species and Inhibits Colon Cancer. PLoS One. 2016;11(4):e0152398. doi: 10.1371/journal.pone.0152398. PubMed [citation] PMID: 27050665, PMCID: PMC4822881
    17. Conrad T, Albrecht AS, de Melo Costa VR, Sauer S, Meierhofer D, Ørom UA. Serial interactome capture of the human cell nucleus. Nat Commun. 2016 Apr 4;7:11212. doi: 10.1038/ncomms11212. PubMed [citation] PMID: 27040163, PMCID: PMC4822031
    18. Telorac J, Prykhozhij SV, Schöne S, Meierhofer D, Sauer S, Thomas-Chollier M, Meijsing SH. Identification and characterization of DNA sequences that prevent glucocorticoid receptor binding to nearby response elements. Nucleic Acids Res. 2016 Mar 25. doi:pii: gkw203. [Epub ahead of print] PubMed [citation] PMID: 27016732
    19. Rosenbaum C, Schick MA, Wollborn J, Heider A, Scholz CJ, Cecil A, Niesler B, Hirrlinger J, Walles H, Metzger M. Activation of Myenteric Glia during Acute Inflammation In Vitro and In Vivo. PLoS One. 2016;11(3):e0151335. doi: 10.1371/journal.pone.0151335. PubMed [citation] PMID: 26964064, PMCID: PMC4786261
    20. Volckmar AL, Han CT, Pütter C, Haas S, Vogel CI, Knoll N, Struve C, Göbel M, Haas K, Herrfurth N, Jarick I, Grallert H, Schürmann A, Al-Hasani H, Hebebrand J, Sauer S, Hinney A. Analysis of Genes Involved in Body Weight Regulation by Targeted Re-Sequencing. PLoS One. 2016;11(2):e0147904. doi: 10.1371/journal.pone.0147904. PubMed [citation] PMID: 26828654, PMCID: PMC4734691
    21. Kremer LS, Distelmaier F, Alhaddad B, Hempel M, Iuso A, Küpper C, Mühlhausen C, Kovacs-Nagy R, Satanovskij R, Graf E, Berutti R, Eckstein G, Durbin R, Sauer S, Hoffmann GF, Strom TM, Santer R, Meitinger T, Klopstock T, Prokisch H, Haack TB. Bi-allelic Truncating Mutations in TANGO2 Cause Infancy-Onset Recurrent Metabolic Crises with Encephalocardiomyopathy. Am J Hum Genet. 2016 Feb 4;98(2):358-62. doi: 10.1016/j.ajhg.2015.12.009. Epub 2016 Jan 21. PubMed [citation] PMID: 26805782, PMCID: PMC4746337
    22. Schmidt M, Scholz CJ, Polednik C, Roller J. Spheroid-based 3-dimensional culture models: Gene expression and functionality in head and neck cancer. Oncol Rep. 2016 Apr;35(4):2431-40. doi: 10.3892/or.2016.4581. Epub 2016 Jan 21. PubMed [citation] PMID: 26797047
    23. Westermann AJ, Förstner KU, Amman F, Barquist L, Chao Y, Schulte LN, Müller L, Reinhardt R, Stadler PF, Vogel J. Dual RNA-seq unveils noncoding RNA functions in host-pathogen interactions. Nature. 2016 Jan 28;529(7587):496-501. doi: 10.1038/nature16547. Epub 2016 Jan 20. PubMed [citation] PMID: 26789254
    24. Busch A, Busch M, Scholz CJ, Kellersmann R, Otto C, Chernogubova E, Maegdefessel L, Zernecke A, Lorenz U. Aneurysm miRNA Signature Differs, Depending on Disease Localization and Morphology. Int J Mol Sci. 2016 Jan 12;17(1). doi:pii: E81.10.3390/ijms17010081. PubMed [citation] PMID: 26771601, PMCID: PMC4730325
    25. Lopes F, Barbosa M, Ameur A, Soares G, de Sá J, Dias AI, Oliveira G, Cabral P, Temudo T, Calado E, Cruz IF, Vieira JP, Oliveira R, Esteves S, Sauer S, Jonasson I, Syvänen AC, Gyllensten U, Pinto D, Maciel P. Identification of novel genetic causes of Rett syndrome-like phenotypes. J Med Genet. 2016 Mar;53(3):190-9. doi: 10.1136/jmedgenet-2015-103568. Epub 2016 Jan 6. PubMed [citation] PMID: 26740508
    26. Weidner C, Rousseau M, Micikas RJ, Fischer C, Plauth A, Wowro SJ, Siems K, Hetterling G, Kliem M, Schroeder FC, Sauer S. Amorfrutin C Induces Apoptosis and Inhibits Proliferation in Colon Cancer Cells through Targeting Mitochondria. J Nat Prod. 2016 Jan 22;79(1):2-12. doi: 10.1021/acs.jnatprod.5b00072. Epub 2016 Jan 5. PubMed [citation] PMID: 26731300
    27. Ronchi CL, Peverelli E, Herterich S, Weigand I, Mantovani G, Schwarzmayr T, Sbiera S, Allolio B, Honegger J, Appenzeller S, Lania AG, Reincke M, Calebiro D, Spada A, Buchfelder M, Flitsch J, Strom TM, Fassnacht M. Landscape of somatic mutations in sporadic GH-secreting pituitary adenomas. Eur J Endocrinol. 2016 Mar;174(3):363-72. doi: 10.1530/EJE-15-1064. Epub 2015 Dec 23. PubMed [citation] PMID: 26701869
    28. Cui H, Schlesinger J, Schoenhals S, Tönjes M, Dunkel I, Meierhofer D, Cano E,Schulz K, Berger MF, Haack T, Abdelilah-Seyfried S, Bulyk ML, Sauer S, Sperling SR. Phosphorylation of the chromatin remodeling factor DPF3a induces cardiac hypertrophy through releasing HEY repressors from DNA. Nucleic Acids Res. 2016 Apr 7;44(6):2538-53. doi: 10.1093/nar/gkv1244. Epub 2015 Nov 17. PubMed [citation] PMID: 26582913, PMCID: PMC4824069
    29. Klein KM, Pendziwiat M, Cohen R, Appenzeller S, de Kovel CG, Rosenow F, Koeleman BP, Kuhlenbäumer G, Sheintuch L, Veksler R, Friedman A, Afawi Z, Helbig I. Autosomal dominant epilepsy with auditory features: a new LGI1 family including a phenocopy with cortical dysplasia. J Neurol. 2016 Jan;263(1):11-6. doi: 10.1007/s00415-015-7921-2. Epub 2015 Oct 12. PubMed [citation] PMID: 26459092
    30. Briese M, Saal L, Appenzeller S, Moradi M, Baluapuri A, Sendtner M. Whole transcriptome profiling reveals the RNA content of motor axons. Nucleic Acids Res. 2016 Feb 29;44(4):e33. doi: 10.1093/nar/gkv1027. Epub 2015 Oct 12. PubMed [citation] PMID: 26464439, PMCID: PMC4770199
    31. Weber H, Richter J, Straube B, Lueken U, Domschke K, Schartner C, Klauke B, Baumann C, Pané-Farré C, Jacob CP, Scholz CJ, Zwanzger P, Lang T, Fehm L, Jansen  A, Konrad C, Fydrich T, Wittmann A, Pfleiderer B, Ströhle A, Gerlach AL, Alpers GW, et al. Allelic variation in CRHR1 predisposes to panic disorder: evidence for biased fear processing. Mol Psychiatry. 2016 Jun;21(6):813-22. doi: 10.1038/mp.2015.125. Epub 2015 Sep 1. PubMed [citation] PMID: 26324098

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